drugset / Trial / NCT03680573
The Effect of Antioxidants on Skin Blood Flow-BH4
RandomizedParallel-groupOpen-labelBasic science
Summary
The goal of this study is to examine possible mechanisms of heightened vasoconstriction in Black/African American men and women as possible links to the elevated prevalence of cardiovascular dysfunction and disease. The main targets in this study are sources of oxidative stress
Timeline
- Start
- 2018-01-08
- Primary completion
- 2018-05-05
- Completion
- 2018-05-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Allopurinol | Small molecule | 10 unknown | — |
| Subject | Apocynin | Small molecule | 100 unknown | — |
| Subject | BH4 | Unknown | 10 unknown | — |
| Background | Acetyl-ß-methylcholine chloride | Unknown | — | — |
| Background | L-NAME | Unknown | — | — |
| Background | Sodium Nitroprusside | Unknown | — | — |