drugset / Trial / NCT03681691
The Interaction Between Diabetes and Estradiol on Human Brain Metabolism in Postmenopausal Women
Phase 1
Completed
12 enrolled
Wake Forest University Health Sciences
National Institute on Aging (NIA) · collab
Non-randomizedParallel-groupOpen-labelOther
Summary
The primary aim of this study is to test whether type 2 diabetes interacts with estradiol on brain metabolism in vivo in humans. This will be accomplished by imaging brain metabolism using positron emission tomography before and after short-term administration of transdermal 17β-estradiol in 10 postmenopausal women with diabetes and 10 non-diabetic postmenopausal women.
Timeline
- Start
- 2019-05-13
- Primary completion
- 2021-07-19
- Completion
- 2021-07-19
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Estradiol | Other / unclassified | — | Other |