drugset / Trial / NCT03682497
Study in HFpEF Patients to Compare the Effect of AZD9977 and Spironolactone on Serum Potassium
RandomizedParallel-groupOpen-labelTreatment
Summary
This is a Phase I, Multicentre study to Compare the Effect of AZD9977 and Spironolactone on Serum Potassium \[sK+\] during 28 days in Patients with HFmrEF or HFpEF and eGFR in the range of ≥40 and ≤70 mL/min/1.73m2.
Timeline
- Start
- 2018-11-01
- Primary completion
- 2020-03-31
- Completion
- 2020-03-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Spironolactone | Small molecule | — | Oral |
| Subject | balcinrenone | Small molecule | — | Oral |