drugset / Trial / NCT03698695
A Pharmacodynamics, Safety, and Pharmacokinetics Study of THN201 Versus Donepezil in Healthy Male Volunteers
RandomizedParallel-groupTriple-blindTreatment
Summary
This study explores the safety, pharmacodynamics and pharmacokinetics of THN201 a combination of donepezil and mefloquine to improve cognitive function in healthy male volunteers after impairment by a scopolamine challenge.
Timeline
- Start
- 2018-09-27
- Primary completion
- 2019-10-20
- Completion
- 2019-12-20
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Donepezil | Small molecule | 5 mg | Oral |
| Subject | Mefloquine | Unknown | 10 mg | Oral |