drugset / Trial / NCT03699293
NSAIDs vs. Coxibs in the Presence of Aspirin
RandomizedCrossoverOpen-labelBasic science
Summary
The objectives of this single site, randomized, crossover study is to evaluate the pharmacodynamic interactions between aspirin, NSAIDs and Coxibs with respect to platelet function, biomarkers of inflammation and endothelial function.
Timeline
- Start
- 2018-09-22
- Primary completion
- 2022-12-01
- Completion
- 2023-01-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Aspirin | Small molecule | 81 mg | Oral |
| Comparator | Celecoxib | Other / unclassified | 200 mg | Oral |
| Comparator | Naproxen | Small molecule | 550 mg | Oral |