drugset / Trial / NCT03704441

ED50 and ED95 of Intrathecal Hyperbaric Bupivacaine With Fentanyl for Transurethral Prostatectomy in Elderly Patients

NCT03704441 ↗

RandomizedParallel-groupOpen-labelTreatment

Summary

As people age, the incidence of prostate hyperplasia increases. So patients under Transurethral Resection of Prostate(TURP) or Holmium Laser Ennucleation of Prostate(HoLEP) are mostly ole age people. Most old age patient has several underlying disease. So patients can develop high mortality and morbidity. Most surgeries for Prostate Resection are taken under Spinal anesthesia. Adequate block level for Prostate Resection is T10. But sometimes, old age patients can develop severe complication after spinal anesthesia. So we started this study to know the adequate drug concentration for Spinal anesthesia taken for Prostate Resection surgery.

Timeline

Start
2018-11-01
Primary completion
2020-05-31
Completion
2020-09-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Bupivacaine Other / unclassified 6 mg Intrathecal
Subject Bupivacaine Other / unclassified 7 mg Intrathecal
Subject Bupivacaine Other / unclassified 8 mg Intrathecal
Subject Bupivacaine Other / unclassified 9 mg Intrathecal
Subject Bupivacaine Other / unclassified 10 mg Intrathecal
Subject Bupivacaine Other / unclassified 11 mg Intrathecal
Subject Bupivacaine Other / unclassified 12 mg Intrathecal

Indications

No indication recorded.