drugset / Trial / NCT03710187

HCT+F vs. HCT Alone in Critically Ill Medical Septic Shock Patients

NCT03710187

Phase 2 Completed 84 enrolled University of Tennessee Medical Center
RandomizedParallel-groupOpen-labelTreatment

Summary

This study will be conducted as a single-center, prospective, open-label, randomized trial that will evaluate adult patients admitted with septic shock to the medical critical care unit (MCC). The objective of the study is to determine if the use of hydrocortisone plus fludrocortisone is associated with a faster resolution of shock (defined as 24 hours vasopressor free) when compared to the use of hydrocortisone alone in medical, critically ill septic shock patients.

Timeline

Start
2018-11-05
Primary completion
2019-09-27
Completion
2019-09-27

Drugs

EvaluationDrugModalityDoseRoute
Subject Fludrocortisone Other / unclassified 50 ug Oral
Subject Hydrocortisone Other / unclassified 50 mg Intravenous