drugset / Trial / NCT03710343
Metformin for Motor and Cognitive Improvement in Children With Cerebral Palsy: A Feasibility Study
Phase 2
Completed
3 enrolled
Holland Bloorview Kids Rehabilitation Hospital
The Hospital for Sick Children · collab
NaSingle-groupOpen-labelTreatment
Summary
The study design is a single-subject ABA clinical trial that is investigating the feasibility including adherence, safety and tolerability of metformin in children aged 5 to 18 years with cerebral palsy (CP). ABA refers to Phase A1 with no metformin, Phase B with metformin, and Phase A2 with no metformin. Secondarily, the study is exploring whether metformin has possible health benefits for improving motor function and cognition.
Timeline
- Start
- 2023-11-14
- Primary completion
- 2025-04-11
- Completion
- 2025-04-24
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Metformin | Small molecule | — | Oral |