Hyperfractionated RT With BCNU Versus Conventional RT With BCNU for Supratentorial Malignant Glioma

Summary

Hyperfractionated radiation therapy (RT) to 72.0 Gy with BCNU will be compared to conventional radiation therapy to 60.0 Gy with BCNU to determine if hyperfractionated RT can improve the median survival time of adults with supratentorial malignant gliomas.

Timeline

Start

1990-11-09

Primary completion

1994-03-15

Completion

2002-10-18

Publications

• Brown MH, Cherng HR, Assif JW, Sun K, Mishra MV. Conditional Survival Estimates for Malignant Glioma Patients: Secondary Analysis of RTOG 9006. Am J Clin Oncol. 2026 Jun 1;49(6):264-267. doi: 10.1097/COC.0000000000001296. Epub 2026 Mar 19.

Drugs

Indications