drugset / Trial / NCT03726242
Peripheral Nociceptive Effects of Levcromakalim
RandomizedCrossoverQuadruple-blindOther
Summary
Intradermal and intramuscular injection of levcromacalim and placebo (sterile saline) on the forehead and forearm of healthy subjects and the following will be investigated: 1. Prevalence and intensity of pain 2. Prevalence and intensity of itching 3. Occurrence and intensity of local redness and swelling 4. Occurrence and intensity of local changes in skin temperature and blood flow
Timeline
- Start
- 2018-11-01
- Primary completion
- 2019-01-20
- Completion
- 2019-01-20
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Levcromakalim | Small molecule | 0.05 ml | Intrathecal |
| Comparator | Levcromakalim | Small molecule | 150 ug/ml | Intrathecal |
| Comparator | Levcromakalim | Small molecule | 0.2 ml | Intrathecal |
Indications
No indication recorded.