Drugs / Levcromakalim
Trials 2 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| — | NCT05889442 | Mar → Jun 2023 | migraine without aura | Danish Headache Center | Completed | No outcome recorded |
| — | NCT05243953 | Mar → Jul 2022 | — | Danish Headache Center | Completed | No outcome recorded |
Also used as a comparator or background therapy in 10 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase not applicable10 trials | ||||||
| — | NCT05565001 Comparator | Sep 2022 → Jul 2023 | migraine with aura, migraine without aura | Danish Headache Center | Unknown | No outcome recorded |
| — | NCT05211050 Comparator | Mar 2022 → Nov 2023 | migraine without aura | Danish Headache Center | Completed | No outcome recorded |
| — | NCT04905654 Comparator | Sep 2021 → May 2023 | migraine disorder | Danish Headache Center | Completed | No outcome recorded |
| — | NCT05093582 Comparator | Jun 2021 → Sep 2022 | cluster headache syndrome | Danish Headache Center | Completed | No outcome recorded |
| — | NCT04853797 Comparator | May 2021 → Jul 2025 | migraine without aura | Danish Headache Center | Completed | No outcome recorded |
| — | NCT04012047 Comparator | Jul → Dec 2019 | migraine disorder | Danish Headache Center | Completed | No outcome recorded |
| — | NCT03886922 Comparator | Apr 2019 → Aug 2023 | headache disorder | Danish Headache Center | Unknown | No outcome recorded |
| — | NCT03726242 Comparator | Nov 2018 → Jan 2019 | — | Danish Headache Center | Completed | No outcome recorded |
| — | NCT03609008 Comparator | Jun → Aug 2018 | headache disorder | Danish Headache Center | Completed | No outcome recorded |
| — | NCT03228355 Comparator | May → Nov 2017 | migraine disorder | Danish Headache Center | Completed | No outcome recorded |
Evidence & citations 5 cited values
Every value below carries the sentence it was read from. 14 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Levcromakalim | ClinicalTrials.gov intervention name — accepted as the source's own label NCT05889442 ↗ |
| Known as | BRL-38227 | ChEMBL registry synonym — accepted as the source's own label CHEMBL100 ↗ |
| Action | Activate | “ATP-sensitive potassium (KATP ) channel opener levcromakalim induces migraine attacks in migraine patients.” PMID 31535367 ↗ Sep 2019 |
| Modality | Small molecule | — CHEMBL100 ↗ |
| Route | Intravenous | “Intravenous administration of levcromakalim or placebo for 20 minutes.” NCT03609008 ↗ |