drugset / Trial / NCT03726788
Intra Articular Injection of Botulinum Toxin Versus Corticoids in Gonarthrosis
RandomizedParallel-groupQuadruple-blindTreatment
Summary
We believe we can demonstrate a link between the analgesic action of intra-articular injection of botulinum toxin and synovial inflammation by Dynamic Contrast Enhancement (DCE) perfusion Magnetic Resonance Imaging (MRI).
Timeline
- Start
- 2019-09
- Primary completion
- 2021-11
- Completion
- 2022-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Botulinum toxin type A | Protein / enzyme biologic | 100 iu | Other |
| Subject | Botulinum toxin type A | Protein / enzyme biologic | 200 iu | Other |
| Comparator | Triamcinolone Hexacetonide | Other / unclassified | 20 mg/ml | Other |