Laparoscopic Assisted Plane Block (LAPB) Trial
Summary
This study attempts to demonstrate improvement in analgesia in a more diverse laparoscopic surgery group with the use of laparoscopic assisted transversus abdominis plane blocks. The investigators will compare bupivacaine (treatment arm 1) versus liposomal bupivacaine (treatment arm 2) versus port site injection of local anesthesia with injection of saline placebo (control). The hypothesis is that liposomal bupivacaine will result in improved analgesia when compared to bupivacaine LAPB and control. The investigators further hypothesize that bupivacaine LAPB will be more effective than the control.
Timeline
- Start
- 2019-02-04
- Primary completion
- 2021-04-14
- Completion
- 2021-04-14
Outcome
Outcome not reported
Stopped (Enrollment): “There were not enough attendings/residents working on the study throughout the COVID-19 pandemic in order to enroll the number of patients required to meet statistical significance.”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Bupivacaine | Other / unclassified | 250 mg | — |
| Comparator | Bupivacaine | Other / unclassified | 266 mg | — |