drugset / Trial / NCT03730402

Laparoscopic Assisted Plane Block (LAPB) Trial

NCT03730402 ↗

Phase 4 Terminated 34 enrolled Santa Barbara Cottage Hospital
RandomizedParallel-groupSingle-blindOther

Summary

This study attempts to demonstrate improvement in analgesia in a more diverse laparoscopic surgery group with the use of laparoscopic assisted transversus abdominis plane blocks. The investigators will compare bupivacaine (treatment arm 1) versus liposomal bupivacaine (treatment arm 2) versus port site injection of local anesthesia with injection of saline placebo (control). The hypothesis is that liposomal bupivacaine will result in improved analgesia when compared to bupivacaine LAPB and control. The investigators further hypothesize that bupivacaine LAPB will be more effective than the control.

Timeline

Start
2019-02-04
Primary completion
2021-04-14
Completion
2021-04-14

Outcome

Outcome not reported

Stopped (Enrollment): “There were not enough attendings/residents working on the study throughout the COVID-19 pandemic in order to enroll the number of patients required to meet statistical significance.”

Drugs

EvaluationDrugModalityDoseRoute
Comparator Bupivacaine Other / unclassified 250 mg —
Comparator Bupivacaine Other / unclassified 266 mg —