drugset / Trial / NCT03730766

Analysis of the Impact of Helicobacter Pylori on Salivary Microbiome in Adults

NCT03730766

NaSingle-groupOpen-labelBasic science

Summary

Helicobacter pylori (H. pylori), a bacteria transmitted from human to human through upper digestive tract as well as fecal-oral transmission, had infected more than half of people around the world. However, the quantity of H. pylori in oral cavity and its influence on oral microbiota remains to be unclear. The aim of the present study was to examine the effects of H. pylori infection as well as its eradication on oral microbiota.

Timeline

Start
2018-08-01
Primary completion
2018-11-15
Completion
2018-11-20

Drugs

EvaluationDrugModalityDoseRoute
Subject Amoxicillin Other / unclassified 1 g
Subject Bismuth Potassium Citrate Unknown 600 mg
Subject Esomeprazole Small molecule 20 mg
Subject Metronidazole Small molecule 0.4 g