drugset / Trial / NCT03733132
Metformin Effect on Brain Function in Insulin Resistant Elderly People
RandomizedParallel-groupQuadruple-blindBasic science
Summary
Alzheimer's disease (AD) and other forms of dementia are rapidly increasing with the aging of the population, and show a clear preponderance among people with insulin resistance. Metformin, an insulin sensitizer, is being examined in clinical trials as an anti-aging drug. However, very little objective data is available regarding metformin's effect on the brain, a major organ affected by aging.
Timeline
- Start
- 2019-03-15
- Primary completion
- 2023-04-05
- Completion
- 2023-04-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Metformin | Small molecule | 2500 mg | Oral |