drugset / Trial / NCT03733652
Optimal Treatment for Poor Efficacy of Entecavir in Chronic Hepatitis B Patients
RandomizedParallel-groupOpen-labelTreatment
Summary
There are chronic hepatitis B patients with poor antiviral efficacy of entecavir in clinical practice. Tenofovir or interferon alfa is the optimal choice right now. The aim of this study is to investigate the therapeutic effect of using tenofovir of interferon alfa in these patients.
Timeline
- Start
- 2018-11-15
- Primary completion
- 2021-09-30
- Completion
- 2021-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | interferon alfa | Protein / enzyme biologic | 180 ug | Other |