drugset / Trial / NCT03756818

TAK-659 and Paclitaxel in Treating Patients With Advanced Solid Tumors

NCT03756818

NaSingle-groupOpen-labelTreatment

Summary

This phase I trial studies the best dose and side effects of TAK-659 and paclitaxel in treating patients with advanced solid tumors. TAK-659 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving TAK-659 and paclitaxel may work better in treating patients with advanced solid tumors.

Timeline

Start
2019-03-05
Primary completion
2023-02-23
Completion
2023-02-23

Drugs

EvaluationDrugModalityDoseRoute
Subject Paclitaxel Small molecule Intravenous
Subject mivavotinib Small molecule Oral

Indications