drugset
drugset / Trial / NCT03781323

Neoadjuvant FOLFOX Therapy With Short Course Radiation and Active Surveillance in Locally Advanced Rectal Cancer

NCT03781323 ↗

Phase 2 Active not recruiting 12 enrolled University of Rochester
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to evaluate the treatment of patients with locally advanced rectal cancer for complete response to neoadjuvant chemotherapy without the use of radiation and surgery.

Timeline

Start
2019-05-03
Primary completion
2022-06-01
Completion
2027-06-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Leucovorin Small molecule 400 mg/m2 Intravenous
Subject Oxaliplatin Small molecule 85 mg/m2 Intravenous
Subject fluorouracil Small molecule 400 mg/m2 Intravenous
Subject fluorouracil Small molecule 2400 mg/m2 Intravenous

Indications

rectal cancer