drugset / Trial / NCT03781960

Abemaciclib and Nivolumab for Subjects With Hepatocellular Carcinoma

NCT03781960

Phase 2 Terminated 7 enrolled Abramson Cancer Center at Penn Medicine
NaSingle-groupOpen-labelTreatment

Summary

The main purpose of this study is to evaluate the effectiveness of the combination of nivolumab and abemaciclib for the treatment of hepatocellular carcinoma. Other goals of this study are to learn about the side effects that this combination of drugs may cause and to learn more about how these drugs work by studying blood and tissue.

Timeline

Start
2019-07-31
Primary completion
2022-04-29
Completion
2022-04-29

Drugs

EvaluationDrugModalityDoseRoute
Subject Abemaciclib Small molecule 150 mg Oral
Subject Nivolumab Monoclonal antibody 480 mg Intravenous