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drugset / Trial / NCT03782233

Study on the Level of Neuromuscular Blockade

NCT03782233 ↗

Completed 83 enrolled The First Affiliated Hospital with Nanjing Medical University Wu Jieping Medical Foundation · collab
RandomizedParallel-groupOpen-labelTreatment

Summary

On the basis of moderate pneumoperitoneum pressure(10 mmHg), this study evaluates the effect of different level of neuromuscular blockade to gastrointestinal barrier function during laparoscopic gastrectomy. 83 patients are randomized to 2 arms ,The patients in deep neuromuscular blockade group（group D, PTC=1-2）will receive high dose rocuronium (0.5-0.6 mg/kg/h) ;While the patients in moderate neuromuscular blockade group（group M, TOF=1-2）will receive moderate dose rocuronium (0.2-0.3 mg/kg/h)

Timeline

Start
2019-01-01
Primary completion
2019-07-31
Completion
2019-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Rocuronium Other / unclassified 0.2 mg/kg Intravenous
Subject Rocuronium Other / unclassified 0.3 mg/kg Intravenous
Subject Rocuronium Other / unclassified 0.5 mg/kg Intravenous
Subject Rocuronium Other / unclassified 0.6 mg/kg Intravenous

Indications

No indication recorded.