Effect of Stimulant Drugs on Social Perception

Phase 1 Completed 36 enrolled University of Chicago

RandomizedCrossoverDouble-blindBasic science

Summary

The study will improve our understanding of the "prosocial" effects of ± 3,4-Methylenedioxymethamphetamine (MDMA), relative to a prototypical stimulant, methamphetamine (MA). The investigators seek to characterize the "uniquely social" effects of MDMA.

Timeline

Start: 2016-06-01
Primary completion: 2018-08-01
Completion: 2018-08-01

Publications

Bershad AK, Hsu DT, de Wit H. MDMA enhances positive affective responses to social feedback. J Psychopharmacol. 2024 Mar;38(3):297-304. doi: 10.1177/02698811231224153. Epub 2024 Jan 27.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Methamphetamine	Small molecule	20 mg	—
Subject	Midomafetamine	Unknown	0.75 mg/kg	—
Subject	Midomafetamine	Unknown	1.5 mg/kg	—

Indications

No indication recorded.