drugset / Trial / NCT03810339

Toripalimab(JS001) as Monotherapy in Participants With POLE or POLD-1 Mutated and Non-MSI-H Advanced Solid Tumors

NCT03810339 ↗

Phase 2 Recruiting 35 enrolled Sun Yat-sen University
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to evaluate the response of toripalimab (JS001), a PD1 antibody, in participants with POLE or POLD-mutated and non microsatellite instability (non-MSI-H) advanced solid cancers.

Timeline

Start
2019-01-15
Primary completion
2028-01-15
Completion
2029-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Toripalimab Monoclonal antibody 240 mg —

Indications