Drugs / Toripalimab
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Toripalimab

Monoclonal antibody targets PDCD1 via inhibition

Developed for
nasopharyngeal carcinoma · non-small cell lung carcinoma · hepatocellular carcinoma · esophageal squamous cell carcinoma · head and neck squamous cell carcinoma · cancer · melanoma · colorectal cancer
+127 more · neoplasm · triple-negative breast carcinoma · small cell lung carcinoma · biliary tract cancer · cervical cancer · gastric cancer · breast cancer · esophageal cancer · gastric adenocarcinoma · urothelial carcinoma · intrahepatic cholangiocarcinoma · gastroesophageal junction adenocarcinoma · mucosal melanoma · renal cell carcinoma · urinary bladder cancer · infiltrating bladder urothelial carcinoma · malignant pancreatic neoplasm · rectal cancer · renal pelvis/ureter urothelial carcinoma · urinary bladder carcinoma · clear cell renal carcinoma · lung cancer · metastasis from malignant tumor of colon · soft tissue sarcoma · colorectal carcinoma · digestive system cancer · digestive system carcinoma · head and neck cancer · Her2-receptor negative breast cancer · hormone receptor-positive breast cancer · hypopharyngeal carcinoma · hypopharynx cancer · hypopharynx squamous cell carcinoma · larynx cancer · lymphoma · metastatic melanoma · oral cavity squamous cell carcinoma · renal cell adenocarcinoma · acral lentiginous melanoma · adenocarcinoma · biliary tract neoplasm · cholangiocarcinoma · cutaneous melanoma · endometrial cancer · esophageal small cell neuroendocrine carcinoma · extranodal nasal NK/T cell lymphoma · gallbladder cancer · gastric carcinoma · gestational trophoblastic neoplasm · kidney cancer · laryngeal squamous cell carcinoma · liver cancer · metastatic malignant neoplasm · metastatic neoplasm · neuroendocrine neoplasm · oral cavity cancer · ovarian cancer · ovarian carcinoma · pancreas disorder · pancreatic ductal adenocarcinoma · pancreatic neoplasm · rectum adenocarcinoma · undifferentiated pleomorphic sarcoma · acute myeloid leukemia · adenocarcinoma of gallbladder and extrahepatic biliary tract · anal canal cancer · anal squamous cell carcinoma · bladder carcinoma in situ · breast neoplasm · cancer of unknown primary site · carcinoma of esophagus · carcinoma of the ampulla of vater · castration-resistant prostate carcinoma · classic Hodgkin lymphoma · collecting duct carcinoma · colon carcinoma · colonic neoplasm · colorectal adenocarcinoma · dermatofibrosarcoma protuberans · diffuse large B-cell lymphoma · distal biliary tract carcinoma · Epstein-Barr virus infection · Epstein-Barr virus-associated gastric carcinoma · exocrine pancreatic carcinoma · gastric neoplasm · gastroesophageal adenocarcinoma · gastroesophageal cancer · hilar cholangiocarcinoma · Hodgkins lymphoma · human papillomavirus-related squamous cell carcinoma · impaired renal function disease · kidney medullary carcinoma · laryngeal carcinoma · lung sarcomatoid carcinoma · Lynch syndrome · malignant epithelial tumor of salivary glands · malignant pleural mesothelioma · malignant urinary system neoplasm · nasal cavity and paranasal sinus carcinoma · nasal cavity and paranasal sinus squamous cell carcinoma · nasopharyngeal squamous cell carcinoma · neoplastic disease or syndrome · neoplastic meningitis · neuroendocrine carcinoma · non-invasive bladder urothelial carcinoma · oropharyngeal carcinoma · oropharynx cancer · oropharynx squamous cell carcinoma · pancreatic adenocarcinoma · paranasal sinus neoplasm · penile carcinoma · portal vein thrombosis · primary peritoneal carcinoma · rectal carcinoma · renal carcinoma · salivary gland carcinoma · sarcoma · scrotum Paget disease · sinonasal undifferentiated carcinoma · skull base neoplasm · squamous cell carcinoma · thymic epithelial neoplasm · thyroid cancer · trachea squamous cell carcinoma · tumor of salivary gland · uterine adnexa cancer · uterine carcinoma
Investigated by
Shanghai Junshi Bioscience Co., Ltd. · Sun Yat-sen University · Fudan University · Tianjin Medical University Cancer Institute and Hospital · Peking Union Medical College Hospital · Coherus Oncology, Inc.
+278 more · Peking University Cancer Hospital & Institute · Shanghai Zhongshan Hospital · Peking University · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Cancer Institute and Hospital, Chinese Academy of Medical Sciences · Fujian Cancer Hospital · Henan Cancer Hospital · RemeGen Co., Ltd. · First Affiliated Hospital of Zhejiang University · Ruijin Hospital · Nanfang Hospital, Southern Medical University · RenJi Hospital · Shanghai Pulmonary Hospital, Shanghai, China · Zhejiang Cancer Hospital · China Medical University, China · The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School · Xiangya Hospital of Central South University · LaNova Medicines Limited · Second Affiliated Hospital, School of Medicine, Zhejiang University · Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University · Sichuan Cancer Hospital and Research Institute · Eye & ENT Hospital of Fudan University · Sponsor GmbH · The First Affiliated Hospital of Zhengzhou University · Beijing Friendship Hospital · Chinese Academy of Medical Sciences · Fifth Affiliated Hospital, Sun Yat-Sen University · First Affiliated Hospital of Guangxi Medical University · First Affiliated Hospital of Wenzhou Medical University · Jiangxi Provincial Cancer Hospital · Jinling Hospital, China · Mabwell (Shanghai) Bioscience Co., Ltd. · Suzhou Abogen Biosciences Co., Ltd. · Tang-Du Hospital · West China Hospital · Affiliated Cancer Hospital & Institute of Guangzhou Medical University · AnewPharma · Cancer Hospital of Guangxi Medical University · Changhai Hospital · Eastern Hepatobiliary Surgery Hospital · Eucure (Beijing) Biopharma Co., Ltd · Fujian Medical University Union Hospital · Guangdong Provincial People's Hospital · Harbour BioMed (Guangzhou) Co. Ltd. · Nanjing Leads Biolabs Co.,Ltd · Peking University Third Hospital · Shanghai Changzheng Hospital · Shanghai Chest Hospital · Shanghai Jiao Tong University School of Medicine · Shanghai Jiatan Pharmatech Co., Ltd · Shengjing Hospital · Sichuan University · TJ Biopharma Co., Ltd. · Taizhou Hospital · The First Affiliated Hospital of Xiamen University · The First Affiliated Hospital with Nanjing Medical University · TopAlliance Biosciences · Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Yu jiren · Zhongshan People's Hospital, Guangdong, China · Zhujiang Hospital · Affiliated Hospital of Guangdong Medical University · Beijing Bio-Targeting Therapeutics Technology Co., Ltd · CTI Clinical Trial and Consulting Services · Cancer Hospital Chinese Academy of Medical Science, Shenzhen Center · Chia Tai Tianqing Pharmaceutical Group Co., Ltd. · Chinese PLA General Hospital · Chongqing University Cancer Hospital · Dalian Maternity and Child Care Hospital · Dan Feng · First Affiliated Hospital Xi'an Jiaotong University · First Affiliated Hospital, Sun Yat-Sen University · First People's Hospital of Foshan · Gansu Provincial Maternal and Child Health Care Hospital · all 284 on the full record

Regulatory milestones approvals, filings & regulatory actions · 2 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Approved EU (EMA) Loqtorzi — 2024-09-19 europa.eu ↗
Approved US (FDA) LOQTORZI — 2023-10-27 fda.gov ↗

Trials 568 · started per year

today
US approved 2023
EU approved 2024
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2016201720182019202020212022202320242025202620272028
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 09 trials
Phase 0 NCT07683832 Jul 2026 → Dec 2028 expected non-small cell lung carcinoma The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School Not yet recruiting No outcome recorded
Phase 0 NCT07583953 Apr 2026 → Jan 2029 expected cancer Suzhou Abogen Biosciences Co., Ltd. Not yet recruiting No outcome recorded
Phase 0 NCT06980155 May 2025 → Jan 2027 expected acute myeloid leukemia Shanghai Jiao Tong University School of Medicine Recruiting No outcome recorded
Phase 0 NCT06577532 Sep 2024 → Dec 2026 expected malignant pancreatic neoplasm Ruijin Hospital Recruiting No outcome recorded
Phase 0 NCT06496373 Jul 2024 → Jun 2026 overdue pancreas disorder Ruijin Hospital Recruiting No outcome recorded
Phase 0 NCT06380309 May 2024 → Dec 2025 overdue digestive system cancer Peking University Recruiting No outcome recorded
Phase 0 NCT06208033 Jan → Oct 2024 non-small cell lung carcinoma Fujian Cancer Hospital Unknown No outcome recorded
Phase 0 NCT04690036 Jul 2021 → Jan 2023 Epstein-Barr virus infection, disease related to transplantation Beijing Friendship Hospital Unknown No outcome recorded
Phase 0 NCT04046185 Oct 2019 → Oct 2021 uterine carcinoma Shanghai First Maternity and Infant Hospital Unknown No outcome recorded
Phase 158 trials
Phase 1 NCT07853053 Jan 2027 → Dec 2029 expected urinary bladder cancer Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University Not yet recruiting No outcome recorded
Phase 1 NCT07835035 Jul 2026 → Feb 2027 expected urothelial carcinoma Cancer Institute and Hospital, Chinese Academy of Medical Sciences Recruiting No outcome recorded
Phase 1 NCT07550842 Jun 2026 → Apr 2028 expected small cell lung carcinoma Shanghai Best-Link Bioscience, LLC Not yet recruiting No outcome recorded
Phase 1 NCT06283134 Mar 2026 → Dec 2027 expected colorectal cancer China Medical University, China Not yet recruiting No outcome recorded
Phase 1 NCT06882876 Jul 2025 → Jan 2027 expected hepatocellular carcinoma Xiangya Hospital of Central South University Enrolling by invitation No outcome recorded
Phase 1 NCT06832982 Feb 2025 → Feb 2028 expected cancer Shanghai Pushi Medical Science Co. Ltd Recruiting No outcome recorded
Phase 1 NCT06389526 Feb 2025 → May 2028 expected — Coherus Oncology, Inc. Not yet recruiting No outcome recorded
Phase 1 NCT06571422 Oct 2024 → Dec 2026 expected cancer Shanghai Junshi Bioscience Co., Ltd. Active not recruiting No outcome recorded
Phase 1 NCT06283303 Apr 2024 → Nov 2025 metastasis from malignant tumor of colon China Medical University, China Unknown No outcome recorded
Phase 1 NCT06020885 Aug 2023 → Oct 2025 overdue esophageal squamous cell carcinoma Sun Yat-sen University Active not recruiting No outcome recorded
Phase 1/273 trials
Phase 1/2 NCT07559929 Aug 2026 → Jun 2028 expected small cell lung carcinoma Hangzhou DAC Biotechnology Co., Ltd. Recruiting No outcome recorded
Phase 1/2 NCT07508761 Jun 2026 → Dec 2028 expected neoplasm Nanjing Immunophage Biotech Co., Ltd Recruiting No outcome recorded
Phase 1/2 NCT07277322 Jun 2026 → Dec 2028 expected metastasis from malignant tumor of colon Dan Feng Not yet recruiting No outcome recorded
Phase 1/2 NCT07320963 Mar 2026 → Mar 2027 expected nasopharyngeal carcinoma Sun Yat-sen University Not yet recruiting No outcome recorded
Phase 1/2 NCT06781125 Mar 2026 → Mar 2028 expected cancer Immorna Biotherapeutics, Inc. Not yet recruiting No outcome recorded
Phase 1/2 NCT07281716 Dec 2025 → Dec 2028 expected colorectal carcinoma Dan Feng Recruiting No outcome recorded
Phase 1/2 NCT07258979 Nov 2025 → Feb 2028 expected nasopharyngeal carcinoma MediLink Therapeutics (Suzhou) Co., Ltd. Recruiting No outcome recorded
Phase 1/2 NCT07190027 Nov 2025 overdue non-small cell lung carcinoma First Affiliated Hospital of Wenzhou Medical University Not yet recruiting No outcome recorded
Phase 1/2 NCT06682780 Sep 2025 → Dec 2028 expected neoplasm LaNova Medicines Limited Recruiting No outcome recorded
Phase 1/2 NCT07099430 Sep 2025 → Oct 2027 expected melanoma Nanjing Leads Biolabs Co.,Ltd Recruiting No outcome recorded
Phase 2346 trials · 6 met primary · 2 missed
Phase 2 NCT07836049 Dec 2026 → Dec 2030 expected esophageal squamous cell carcinoma Vanderbilt-Ingram Cancer Center Not yet recruiting No outcome recorded
Phase 2 NCT07189793 Dec 2026 → Oct 2027 expected bladder carcinoma in situ First Affiliated Hospital of Wenzhou Medical University Not yet recruiting No outcome recorded
Phase 2 NCT07808216 Oct 2026 → Oct 2028 expected non-invasive bladder urothelial carcinoma Tianjin First Central Hospital Not yet recruiting No outcome recorded
Phase 2 NCT07819578 Oct 2026 → Dec 2028 expected non-small cell lung carcinoma Shaodong Hong Not yet recruiting No outcome recorded
Phase 2 NCT07823270 Oct 2026 → Dec 2028 expected esophageal squamous cell carcinoma Hebei Medical University Fourth Hospital Not yet recruiting No outcome recorded
Phase 2 NCT07796126 Sep 2026 → May 2028 expected head and neck squamous cell carcinoma Barbara Ann Karmanos Cancer Institute Not yet recruiting No outcome recorded
Phase 2 NCT07816770 Sep 2026 → Dec 2027 expected kidney medullary carcinoma Fudan University Not yet recruiting No outcome recorded
Phase 2 NCT07855965 Sep 2026 → Aug 2028 expected non-small cell lung carcinoma West China Hospital Recruiting No outcome recorded
Phase 2 NCT07817095 Sep 2026 → Jan 2029 expected undifferentiated pleomorphic sarcoma Tianjin Medical University Cancer Institute and Hospital Not yet recruiting No outcome recorded
Phase 2 NCT05479045 Sep 2026 → Nov 2027 ovarian carcinoma, uterine adnexa cancer Georgetown University Withdrawn No outcome recorded Stop: Business
Show all 346 trials opens the full record — a long page
Phase 2/37 trials · 1 met primary
Phase 2/3 NCT07653451 Jul 2026 → Dec 2027 expected esophageal squamous cell carcinoma Peking University Cancer Hospital & Institute Not yet recruiting No outcome recorded
Phase 2/3 NCT06984588 Mar 2024 → Aug 2028 expected non-small cell lung carcinoma TJ Biopharma Co., Ltd. Active not recruiting No outcome recorded
Phase 2/3 NCT05817201 Jul 2022 → Dec 2023 esophageal cancer Taizhou Hospital Unknown No outcome recorded
Phase 2/3 NCT05125055 Oct 2021 → Sep 2024 overdue oral cavity squamous cell carcinoma Shanghai Jiao Tong University School of Medicine Recruiting No outcome recorded
Phase 2/3 NCT04669496 Jan 2021 → Apr 2025 overdue intrahepatic cholangiocarcinoma Shanghai Zhongshan Hospital Active not recruiting Met primary
Phase 2/3 NCT03992911 Jun 2019 → Jun 2022 neuroendocrine carcinoma Peking University Unknown No outcome recorded
Phase 2/3 NCT03691454 Jun 2018 → Sep 2026 overdue gastric adenocarcinoma Peking University Active not recruiting No outcome recorded
Phase 358 trials · 9 met primary
Phase 3 NCT07371897 Jun 2026 overdue head and neck squamous cell carcinoma Sun Yat-sen University Not yet recruiting No outcome recorded
Phase 3 NCT07584135 May 2026 → Jan 2029 expected gastric adenocarcinoma NingBo Junyan Hongshi Biosciences Co., Ltd Recruiting No outcome recorded
Phase 3 NCT07540390 May 2026 → Dec 2032 expected nasopharyngeal carcinoma Sun Yat-sen University Not yet recruiting No outcome recorded
Phase 3 NCT07554846 May 2026 → May 2030 expected — Fudan University Recruiting No outcome recorded
Phase 3 NCT07362186 Apr 2026 → Aug 2028 expected gastric adenocarcinoma LaNova Medicines Limited Recruiting No outcome recorded
Phase 3 NCT07445295 Mar 2026 → Jun 2028 expected pancreatic ductal adenocarcinoma Chipscreen Biosciences, Ltd. Not yet recruiting No outcome recorded
Phase 3 NCT07392060 Feb 2026 → Sep 2029 expected cervical cancer Shanghai Jiatan Pharmatech Co., Ltd Not yet recruiting No outcome recorded
Phase 3 NCT06952621 Feb 2026 → Dec 2027 expected esophageal squamous cell carcinoma Tang-Du Hospital Not yet recruiting No outcome recorded
Phase 3 NCT07332221 Jan 2026 → Oct 2029 expected esophageal cancer Henan Cancer Hospital Not yet recruiting No outcome recorded
Phase 3 NCT07246330 Dec 2025 → Dec 2027 expected esophageal squamous cell carcinoma Tianjin Medical University Cancer Institute and Hospital Not yet recruiting No outcome recorded
Phase 42 trials
Phase 4 NCT06457503 Nov 2024 → Dec 2027 expected nasopharyngeal carcinoma Coherus Oncology, Inc. Recruiting No outcome recorded
Phase 4 NCT05291910 Mar 2022 → Dec 2024 breast cancer Chinese Academy of Medical Sciences Unknown No outcome recorded
Phase not applicable15 trials
— NCT07067450 Jul 2025 → Dec 2026 expected esophageal squamous cell carcinoma Sichuan University Not yet recruiting No outcome recorded
— NCT06709274 Nov 2024 → Jan 2029 expected non-small cell lung carcinoma Guangdong Association of Clinical Trials Not yet recruiting No outcome recorded
— NCT06762158 Oct 2024 → Dec 2027 expected esophageal squamous cell carcinoma RenJi Hospital Active not recruiting No outcome recorded
— NCT06371274 Oct 2024 → Apr 2026 overdue triple-negative breast carcinoma First Affiliated Hospital of Zhejiang University Recruiting No outcome recorded
— NCT06313554 May 2024 overdue intrahepatic cholangiocarcinoma Fudan University Not yet recruiting No outcome recorded
— NCT06256224 Feb 2024 → Dec 2028 expected cervical cancer Ruijin Hospital Recruiting No outcome recorded
— NCT06028672 Sep 2023 → Aug 2025 overdue gestational trophoblastic neoplasm Peking Union Medical College Hospital Recruiting No outcome recorded
— NCT05877573 Jul 2023 → Jan 2025 overdue rectal cancer Nanfang Hospital, Southern Medical University Recruiting No outcome recorded
— NCT05478473 Oct 2022 → Aug 2023 melanoma Peking University Cancer Hospital & Institute Unknown No outcome recorded
— NCT05162898 Jan 2022 → Dec 2023 hepatocellular carcinoma Henan Cancer Hospital Unknown No outcome recorded
Comparator or background therapy84 trials
Phase 0 NCT07680582 Background Jun 2026 overdue cancer Ruijin Hospital Recruiting No outcome recorded
Phase 1 NCT07562841 Background Apr 2026 → Apr 2028 expected melanoma West China Hospital Recruiting No outcome recorded
Phase 1 NCT07625423 Background Mar 2026 → Mar 2028 expected nasopharyngeal carcinoma West China Hospital Recruiting No outcome recorded
Phase 1 NCT07004244 Background Jun 2025 → Dec 2027 expected cancer Sichuan University Recruiting No outcome recorded
Phase 1 NCT06896422 Background Jun 2025 → Dec 2026 expected non-small cell lung carcinoma The First Affiliated Hospital of Zhengzhou University Recruiting No outcome recorded

Press releases naming this drug 45 releases

DateIssuerRelease
2026-06-23 Coherus Oncology, Inc. Coherus and Zumutor Biologics Announce Clinical Collaboration to Evaluate ZM008 in Combination with LOQTORZI® (toripalimab-tpzi) coherus.com ↗
2025-05-27 Coherus Oncology, Inc. Coherus Announces Clinical Collaboration with STORM Therapeutics to Evaluate STC-15 in Combination with LOQTORZI® (toripalimab-tpzi) coherus.com ↗
2024-10-10 Harbour BioMed (Guangzhou) Co. Ltd. Harbour BioMed Announces Publication of the Phase I Study Results for Porustobart in Combination with Toripalimab in Advanced Melanoma and Other Solid Tumors harbourbiomed.com ↗
2024-05-08 Coherus Oncology, Inc. Coherus Announces Clinical Collaboration with the Cancer Research Institute for a Novel Combination Evaluating LOQTORZI® (toripalimab-tpzi) with ENB Therapeutics' ENB-003 for the Treatment of Ovarian Cancer coherus.com ↗
2024-01-04 Coherus Oncology, Inc. INOVIO and Coherus Announce Clinical Collaboration to Advance Development of INO-3112 in Combination with LOQTORZI™ (toripalimab-tpzi) coherus.com ↗
2023-12-11 Coherus Oncology, Inc. Coherus Announces Updated NCCN Clinical Practice Guidelines Positioning LOQTORZI™ (toripalimab-tpzi) as Preferred Category 1 Regimen for First-Line Treatment of Cancer of the Nasopharynx coherus.com ↗
2023-11-28 Coherus Oncology, Inc. Coherus and Junshi Biosciences Announce Publication of Positive Final Overall Survival Results of JUPITER-02, a Phase 3 Trial Evaluating LOQTORZI™ (toripalimab-tpzi) as Treatment for Nasopharyngeal Carcinoma, in the Journal of the American Medical Association coherus.com ↗
2023-10-27 Coherus Oncology, Inc. Coherus and Junshi Biosciences Announce FDA Approval of LOQTORZI™ (toripalimab-tpzi) in All Lines of Treatment for Recurrent or Metastatic Nasopharyngeal Carcinoma (NPC) coherus.com ↗
2023-10-14 Coherus Oncology, Inc. Coherus Announces Toripalimab Data at 2023 AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics coherus.com ↗
2023-09-25 Coherus Oncology, Inc. FDA Issues Complete Response Letter (CRL) for UDENYCA® ONBODY™ Biologics License Application Solely Due to an Ongoing Review of Inspection Findings at a Third-Party Filler; Coherus Also Announces Completion of Toripalimab FDA Inspections coherus.com ↗
2023-06-05 Coherus Oncology, Inc. Coherus Announces Positive Final Overall Survival Results of JUPITER-02 Phase 3 Trial Evaluating Toripalimab in Nasopharyngeal Carcinoma coherus.com ↗
2023-05-26 Harbour BioMed (Guangzhou) Co. Ltd. Harbour BioMed Reports Results of Phase Ib Clinical Trial of Porustobart in Combination of Toripalimab in Patients with Hepatocellular Carcinoma at ASCO 2023 harbourbiomed.com ↗

Evidence & citations 17 cited values

Every value below carries the sentence it was read from. 656 sources stand behind the page.

FieldValueCited text
Known as Toripalimab “This is a multicenter, open-Lable, randomized, phase III clinical study to compare the pharmacokinetic profile, efficacy, and safety of Toripalimab injection (subcutaneous)...” NCT06505837 ↗
618

“A Multicenter, Randomized, Double-Blind, Phase III Clinical Study to Evaluate the Efficacy and Safety of Toripalimab Injection Combined With Postoperative Adjuvant Chemotherapy...” NCT05180734 ↗

“PD-1 blockade (comprising tislelizumab <200 mg/cycle>, carrellimab <200 mg/cycle>, or toripalimab <240 mg/cycle>) once every 3 weeks for two years, or until intolerable...” NCT06472713 ↗

“Patients in the experimental arm will first receive one cycle of regorafenib (80 mg once daily on days 1-21 of each 28 days cycle) and toripalimab (240mg, q3w), followed by...” PMID 37869085 ↗ Oct 2023

“This is a Phase 2 study of GV20-0251 in combination with anti-PD-1 monoclonal antibodies (including tislelizumab and toripalimab) for the treatment of participants with...” NCT07623642 ↗

“Toripalimab, a recombinant, humanized programmed death receptor-1 (PD-1) monoclonal antibody that binds to PD-1 and prevents binding of PD-1 with programmed death ligands 1...” NCT05048017 ↗

“Successful organoids undergo drug sensitivity testing against a predefined panel of drugs (Gemcitabine + Cisplatin,Gemcitabine + Oxaliplatin,Durvalumab + Gemcitabine +...” NCT07351591 ↗

“select 1 to 2 of the tumors for JCXH-211 combined with anti-PD-1 antibody dose expansion study with reference to the approved indications of anti-PD-1 antibody (Toripalimab )...” NCT06781125 ↗

“Drug sensitivity testing will be performed on a panel of approved targeted and immunotherapeutic agents (including Apatinib, Atezolizumab + Bevacizumab, Donafenib +...” NCT07363356 ↗

“a) Camrelizumab 200mg, b) Toripalimab 240mg, or c) Adebrelimab 1200mg will be started on day 1 of induction chemotherapy and given every 3 weeks for up to 12 cycles, or until...” NCT06675214 ↗

“Combination phase Anti-PD1 monoclonal antibody: Choose one of the anti-PD-1 monoclonal antibody drugs reimbursed by medical insurance, toripalimab (240mg), camrelizumab...” NCT06259721 ↗

Show 608 more sources

Known as GS+Toripalimab ClinicalTrials.gov intervention name — accepted as the source's own label NCT03796429 ↗
Known as JS-001 “This is a multicenter, open-Lable, randomized, phase III clinical study to compare the pharmacokinetic profile, efficacy, and safety of Toripalimab injection (subcutaneous)...” NCT06505837 ↗
65

“Drug: Toripalimab Toripalimab 240mg every 2 weeks with a total of 2 cycles as neoadjuvant anti-PD-1 immunotherapy; Toripalimab240mg every 3 weeks with a total of 8 cycles as...” NCT03925090 ↗

“Study drug: toripalimab JS001 dosage:240mg Drug administration plan and mode:Intravenous infusion of 30min (not less than 20min and not more than 60min), followed by...” NCT05860335 ↗

“This study aimed to evaluate the efficacy and safety of Toripalimab injection (js001) combined with SBRT radiotherapy and neoadjuvant therapy with or without chemotherapy for...” NCT06293690 ↗

“Toripalimab injection (JS001) is a humanized IgG4 monoclonal antibody against the programmed death-1 (PD-1) receptor, blocks the interaction of PD-1 with its ligands and...” NCT04084158 ↗

“Thus we plan to conduct this prospective phase II clinical trial, evaluating the safety and efficacy of toripalimab, also known as JS001, in combination with XELOX for the...” NCT04119622 ↗

“JS001 or toripalimab, the most leading investigational drug of Juniper Biologics against various malignancies, is a recombinant humanized anti-PD-1 injectable monoclonal antibody” NCT05586100 ↗

“humanized anti-PD-1 monoclonal antibody(JS001) injected intravenously 240mg per 3 weeks until disease progresses or unacceptable tolerability occurs.” NCT03879057 ↗

“Evaluating the Efficacy and Safety of Toripalimab (Recombinant Humanized Anti-PD-1 Monoclonal Antibody, JS001) Versus Placebo as Adjuvant Therapy” NCT03859128 ↗

“Toripalimab Injection (JS001) Combined With Bevacizumab as the First-line Therapy for Advanced Hepatocellular Carcinoma (HCC)” NCT04605796 ↗

“Phase II Study of Toripalimab (JS001) Plus Stereotactic Body Radiotherapy in Colorectal Cancer Patients With Oligometastasis” NCT03927898 ↗

Show 55 more sources

Known as JS001sc “This is a multicenter, open-Lable, randomized, phase III clinical study to compare the pharmacokinetic profile, efficacy, and safety of Toripalimab injection (subcutaneous)...” NCT06505837 ↗
1

“Toripalimab injection(subcutaneous)/JS001sc” NCT05751486 ↗

Known as Recombinant Human Anti-PD1 Monoclonal Antibody Injection “The Recombinant Human GM-CSF Herpes Simplex Virus Injection (OrienX010) in Combination with Recombinant Human Anti-PD1 Monoclonal Antibody Injection (JS001)” NCT04206358 ↗
Known as teriprizumab “PD-1 inhibitors (sintilimab/teriprizumab/camrelizumab) are administered intravenously at a dose of 200 mg once every three weeks.” NCT06991907 ↗
Known as tori “This phase Ib trial study (Clinicaltrials.gov NCT04197882) assessed the efficacy and safety of the combination of neoadjuvant oncolytic virus orienX010 (ori) and anti-PD-1...” PMID 39572525 ↗ Nov 2024
Known as Toripalimab Injection “Toripalimab Injection (JS001)” NCT04568304 ↗
Known as Toripalimab-tpzi ClinicalTrials.gov intervention name — accepted as the source's own label NCT07214987 ↗
1

NCT05479045 ↗

Known as Toripalimab: JS001 “Toripalimab: JS001” NCT07047001 ↗
Known as treprizumab “treprizumab injection 240mg / carrilizumab injection 200mg / Tirelizumab injection 200mg * q21d” NCT05520814 ↗
Known as Tripleitriumab ClinicalTrials.gov intervention name — accepted as the source's own label NCT04527068 ↗
Known as Tuoyi “Toripalimab monoclonal injection (Tuo Yi) combined with axitinib tablet (Inlyta®) as neoadjuvant therapy for localized mucosal melanoma.” NCT04180995 ↗
1

“2. Toripalimab Injection (Tuoyi)” NCT07630363 ↗

Action Inhibit “blocks the interaction of PD-1 with its ligands” PMID 30642373 ↗ Jan 2019
Modality Monoclonal antibody “JS001, a humanized IgG4 monoclonal antibody against the programmed death-1 (PD-1) receptor” PMID 30642373 ↗ Jan 2019
Route Intravenous “single-dose, intravenous infusion of JS001” PMID 30642373 ↗ Jan 2019
Target PDCD1 “anti-PD-1 (toripalimab)” NCT04368273 ↗