drugset / Trial / NCT05173142
A Phase Ib/II Clinical Study Evaluating HMPL-453 Tartrate as Monotherapy and in Combination With Chemotherapy or Toripalimab in Advanced Solid Tumors
Non-randomizedSequentialOpen-labelTreatment
Summary
A Phase Ib/II Clinical Study Evaluating HMPL-453 Tartrate as Monotherapy and in Combination with Chemotherapy or Toripalimab in Advanced Solid Tumors
Timeline
- Start
- 2022-01-22
- Primary completion
- 2025-07-17
- Completion
- 2026-01-17
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cisplatin | Other / unclassified | — | Intravenous |
| Subject | Docetaxel | Small molecule | — | Intravenous |
| Subject | Gemcitabine | Small molecule | — | Intravenous |
| Subject | HMPL-453 | Unknown | — | Oral |
| Subject | Toripalimab | Monoclonal antibody | — | Intravenous |