drugset / Trial / NCT06371274
A Study on the Efficacy and Safety of Oral All-trans Retinoic Acid Combined With Toripalimab in TNBC.
Recruiting
29 enrolled
First Affiliated Hospital of Zhejiang University
Shanghai Longfine Biotechnology Co., Ltd. · collabTopAlliance · collab
NaSingle-groupOpen-labelTreatment
Summary
To evaluate the clinical efficacy and safety of oral all-trans retinoic acid in combination with toripalimab in patients with locally advanced, recurrent, or metastatic triple-negative breast cancer who had failed second-line and subsequent therapy.
Timeline
- Start
- 2024-10-10
- Primary completion
- 2026-04-30
- Completion
- 2026-04-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Toripalimab | Monoclonal antibody | 240 mg | Intravenous |
| Subject | Tretinoin | Small molecule | 150 mg/m2 | Oral |