drugset / Trial / NCT04605185

Donafenib and Toripalimab Combined With TACE in Patients With Unresectable Hepatocellular Carcinoma

NCT04605185

Phase 1 Unknown 18 enrolled Suzhou Zelgen Biopharmaceuticals Co.,Ltd
NaSingle-groupOpen-labelTreatment

Summary

This study is the single-center, open-label phase I clinical trial to evaluate tolerability, safety and efficacy of Donafenib and JS001 in combination with TCAE in patients with Unresectable Hepatocellular Carcinoma.

Timeline

Start
2021-01-08
Primary completion
2024-12
Completion
2024-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Donafenib Small molecule 100 mg Oral
Subject Donafenib Small molecule 150 mg Oral
Subject Toripalimab Monoclonal antibody 240 mg Intravenous