drugset / Trial / NCT06078982

Posterior-line Treatment With Disitamab Vedotin Plus PD-1 in Advanced HER2-low Expressing Gastric Cancer

NCT06078982

Phase 1 Unknown 39 enrolled Shanghai East Hospital
NaSingle-groupOpen-labelTreatment

Summary

This is a single-arm, prospective, non-randomized, multi-center/single-center, open-label, phase I clinical study aimed at evaluating the efficacy and safety of Disitamab Vedotin in combination with PD-1 as posterior line treatment for patients with advanced HER2-low expressing gastric cancer.

Timeline

Start
2023-06-06
Primary completion
2025-08
Completion
2025-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Disitamab Vedotin Monoclonal antibody 2 mg/kg Intravenous
Subject Toripalimab Monoclonal antibody 3 mg/kg

Indications