drugset / Trial / NCT05149027
A Study to Evaluate Safety, Tolerability, PK/PD and Preliminary Efficacy of HBM4003 Combine With Toripalimab in Patients With Advanced HCC and Other Solid Tumors
NaSingle-groupOpen-labelTreatment
Summary
This is an open-label, multi-center phase 1 study. The trial, consisting of Part 1 dose confirmation and Part 2 dose expansion, is designed to evaluate the safety, tolerability, PK/PD and preliminary efficacy of HBM4003 in combination with Toripalimab in patients with advanced HCC and other solid tumors.
Timeline
- Start
- 2021-12-20
- Primary completion
- 2024-05-30
- Completion
- 2024-05-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | PORUSTOBART | Monoclonal antibody | — | — |
| Subject | Toripalimab | Monoclonal antibody | — | — |