drugset / Trial / NCT05149027

A Study to Evaluate Safety, Tolerability, PK/PD and Preliminary Efficacy of HBM4003 Combine With Toripalimab in Patients With Advanced HCC and Other Solid Tumors

NCT05149027

Phase 1 Unknown 67 enrolled Harbour BioMed (Guangzhou) Co. Ltd.
NaSingle-groupOpen-labelTreatment

Summary

This is an open-label, multi-center phase 1 study. The trial, consisting of Part 1 dose confirmation and Part 2 dose expansion, is designed to evaluate the safety, tolerability, PK/PD and preliminary efficacy of HBM4003 in combination with Toripalimab in patients with advanced HCC and other solid tumors.

Timeline

Start
2021-12-20
Primary completion
2024-05-30
Completion
2024-05-30

Drugs

EvaluationDrugModalityDoseRoute
Subject PORUSTOBART Monoclonal antibody
Subject Toripalimab Monoclonal antibody

Indications