drugset / Trial / NCT07332221

Application of Toripalimab as Adjuvant Therapy After Esophageal Cancer Surgery: A Multicenter Clinical Trial

NCT07332221

Phase 3 Not yet recruiting 435 enrolled Henan Cancer Hospital
RandomizedParallel-groupOpen-labelTreatment

Summary

This study is a prospective, multicenter, multi-cohort Phase III clinical trial. It primarily enrolls high-risk recurrent esophageal cancer patients who have undergone R0 resection after neoadjuvant chemoimmunotherapy. Eligible patients are stratified based on pathological lymph node status and receive either toripalimab monotherapy as maintenance treatment or clinical observation only.

Timeline

Start
2026-01-20
Primary completion
2029-10-01
Completion
2031-10-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Toripalimab Monoclonal antibody 240 mg

Indications