drugset / Trial / NCT04229849

Anrotenib Plus Toripalimab Versus Toripalimab in Patients With Advanced Esophageal Squamous Cell Carcinoma

NCT04229849

Phase 2 Unknown 164 enrolled Henan Cancer Hospital
RandomizedParallel-groupOpen-labelTreatment

Summary

The aim of this study is to investigate the efficacy and safety of anrotenib plus toripalimab in the treatment of advanced esophageal squamous cell carcinoma. In addition, the investigators will explore the possible mechanisms of anrotinib combined with toripalimab in advanced esophageal squamous cell carcinoma, and screen out biomarkers that can predict the efficacy of combination therapy.

Timeline

Start
2020-01
Primary completion
2021-01
Completion
2022-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Anrotenib Unknown 10 mg Oral
Comparator Toripalimab Monoclonal antibody 240 mg Intravenous