drugset / Trial / NCT04926532

Toripalimab Plus Sorafenib in Patients With Advanced-Stage Hepatocellular Carcinoma

NCT04926532

Phase 1/2 Unknown 30 enrolled Shanghai Zhongshan Hospital
NaSingle-groupOpen-labelTreatment

Summary

Toripalimab is a programmed cell death protein 1 antibody.This is an open-label, single arm, multi-center exploratory study.The objective of this study is to evaluate the efficacy and safety of therapy with toripalimab and sorafenib in patients with advanced stage hepatocellular carcinoma.

Timeline

Start
2019-08-01
Primary completion
2021-10-31
Completion
2021-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Sorafenib Small molecule Oral
Subject Toripalimab Monoclonal antibody 240 mg Intravenous