drugset / Trial / NCT05650203

A Study of JS009 Monotherapy and JS009 as a Triple Combination Therapy in Patients With Advanced Malignancies

NCT05650203

NaSingle-groupOpen-labelTreatment

Summary

The study is being conducted to evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy JS009 as a monotherapy and JS009 as a Triple Combination Therapy in Combination with Toripalimab and JS006 in Patients with Advanced Malignancies, also to explore the RP2D of JS009.

Timeline

Start
2023-03-31
Primary completion
2025-10-25
Completion
2026-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject JS009 Unknown 18 mg Intravenous
Subject JS009 Unknown 60 mg Intravenous
Subject JS009 Unknown 180 mg Intravenous
Subject JS009 Unknown 600 mg Intravenous
Subject JS009 Unknown 1200 mg Intravenous
Background JS006 Monoclonal antibody 600 mg Intravenous
Background Toripalimab Monoclonal antibody 240 mg Intravenous