drugset / Trial / NCT03810391

Using Preoperative Anxiety Score to Determine the Total Dose of Butorphanol for Sedation

NCT03810391

Phase 2 Completed 126 enrolled Shengjing Hospital
RandomizedParallel-groupQuadruple-blindTreatment

Summary

Orthopedic surgeries are considered to be discomfortable and the sense of fear and anxiety of patients who already have preoperative anxiety may be aggravated by intraoperative stimulation, which may contribute to postoperative complications. Previous studies have found that high anxiety predicts increased sedative requirements. Therefore, the investigators explored the relationship between anxiety and intraoperative butorphanol requirements and the investigators evaluated the specific sedative requirement which can keep satisfactory sedative state for patients by preoperative anxiety score

Timeline

Start
2017-12-01
Primary completion
2018-12-20
Completion
2018-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Butorphanol Other / unclassified 7.5 ug/kg Intravenous

Indications

No indication recorded.