drugset / Trial / NCT03812770
Phase 2 Study of Sorafenib Plus HAIC of FOLFOX vs. Sorafenib Plus HAIC of OXA for Advanced HCC
Phase 2
Unknown
150 enrolled
Sun Yat-sen University
Guangzhou No.12 People's Hospital · collabKaiping Central Hospital · collab
Non-randomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to evaluate the efficacy and safety of hepatic arterial infusion chemotherapy (HAIC) of oxaliplatin plus fluorouracil/leucovorin compared with HAIC of oxaliplatin alone in patients with advanced hepatocellular carcinoma (HCC)
Timeline
- Start
- 2018-08-04
- Primary completion
- 2019-09-01
- Completion
- 2019-09-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Leucovorin | Small molecule | — | Other |
| Comparator | fluorouracil | Small molecule | — | Other |
| Background | Oxaliplatin | Small molecule | — | Other |
| Background | Sorafenib | Small molecule | 400 mg | Oral |