drugset / Trial / NCT03818126
The Del Nido Versus Cold Blood Cardioplegia in Aortic Valve Replacement
RandomizedParallel-groupSingle-blindTreatment
Summary
A group of 150 patients undergoing aortic valve replacement procedure will be randomized either into del Nido cardioprotection protocol (75 participants) or into the cold blood cardioplegia protocol (75 participants). The intraoperative and perioperative outcomes of using each solution will be presented and compared (see the endpoints).
Timeline
- Start
- 2016-07-01
- Primary completion
- 2018-06-30
- Completion
- 2018-07-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | KCl | Unknown | 13 ml | — |
| Subject | KCl | Unknown | 25 ml | — |
| Subject | Lidocaine | Other / unclassified | 13 ml | — |
| Subject | Magnesium Sulfate | Other / unclassified | 4 ml | — |
| Subject | Mannitol | Diagnostic / imaging agent | 16.3 ml | — |
| Subject | Mannitol | Diagnostic / imaging agent | 20 ml | — |
| Subject | Plasmalyte A | Unknown | 435 ml | — |
| Subject | Plasmalyte A | Unknown | 1000 ml | — |
| Subject | sodium bicarbonate | Diagnostic / imaging agent | 13 ml | — |
| Subject | sodium bicarbonate | Diagnostic / imaging agent | 20 ml | — |