drugset / Trial / NCT03823079
Comparison of Interleukin-11 and rhTPO for Recurrent Colorectal Cancer Patients With Thrombocytopenia
RandomizedParallel-groupOpen-labelTreatment
Summary
This randomized controlled clinical phase II study was designed to compare the effect of rhTPO with rhIL-11 in improving thrombocytopenia in patients with recurrent colorectal cancer who underwent radiotherapy and with thrombocytopenia.
Timeline
- Start
- 2019-02-01
- Primary completion
- 2019-09-01
- Completion
- 2020-02-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | recombinant human thrombopoietin | Protein / enzyme biologic | 300 iu/kg | Subcutaneous |
| Comparator | rhIL-11 | Protein / enzyme biologic | 50 ug/kg | Subcutaneous |
| Background | Irinotecan | Small molecule | 65 mg/m2 | — |
| Background | Irinotecan | Small molecule | 80 mg/m2 | — |
| Background | Raltitrexed | Small molecule | 3 mg/m2 | — |