drugset / Trial / NCT03829566

Autologous Transplant To End NMO Spectrum Disorder

NCT03829566

Phase 2/3 Withdrawn Northwestern University
NaSingle-groupOpen-labelTreatment

Summary

This study is designed to treat your disease with an autologous stem cell transplant using a regimen of immune suppressant drugs and chemotherapy to reset your immune system and to determine if your disease will go into long-term remission.

Timeline

Start
2019-11
Primary completion
2025-01
Completion
2025-11-28

Drugs

EvaluationDrugModalityDoseRoute
Subject Autologous Stem Cells Cell therapy
Background 2-MERCAPTOETHANESULFONIC ACID Small molecule
Background Cyclophosphamide Other / unclassified
Background G-CSF Protein / enzyme biologic
Background Immune Globulin Intravenous (Human) Protein / enzyme biologic
Background Methylprednisolone Other / unclassified
Background Rituximab Monoclonal antibody
Background rATG Protein / enzyme biologic

Indications