drugset / Trial / NCT03831932

Telaglenastat Hydrochloride and Osimertinib in Treating Patients With EGFR-Mutated Stage IV Non-small Cell Lung Cancer

NCT03831932

Phase 1/2 Active not recruiting 22 enrolled National Cancer Institute (NCI)
NaSingle-groupOpen-labelTreatment

Summary

This phase Ib trial studies the side effects and best dose of telaglenastat hydrochloride when given together with osimertinib in treating patients with stage IV non-small cell lung cancer and a mutation in the EGFR gene. Telaglenastat hydrochloride and osimertinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Timeline

Start
2020-03-16
Primary completion
2024-06-12
Completion
2027-03-13

Drugs

EvaluationDrugModalityDoseRoute
Subject CB-839 Unknown Oral
Subject Osimertinib Small molecule Oral