Haemodynamic Effects of GLP-1 and Glucagon in Healthy Male Volunteers

Summary

The study seeks to explore the cardiovascular effects of co-agonism at two peptide receptors, GLP-1 and glucagon. Glucagon, exenatide and 0.9% saline will be intravenously infused, both in isolation, and combination into healthy male participants. Overall, the aim of the study is to further our understanding on the role these endogenous substances play (both in isolation and combination) in haemodynamic regulation.

Timeline

Start

2019-02-11

Primary completion

2021-11-01

Completion

2021-11-01

Drugs

Indications