drugset / Trial / NCT03850418

Azacitidine and Chimerism in MDS or AML Patients After Allogeneic Stem Cell Transplant

NCT03850418 ↗

Phase 2 Recruiting 43 enrolled Henry Ford Health System
NaSingle-groupOpen-labelTreatment

Summary

Previous studies provide a rationale for administration of AZA after allo SCT for decreasing chimerism. The investigators hypothesize that azacitidine can be well tolerated after SCT and help decrease rate of decreasing donor chimerism and hence decrease relapse without increasing GVHD

Timeline

Start
2019-07-01
Primary completion
2028-02-20
Completion
2028-02-20

Drugs

EvaluationDrugModalityDoseRoute
Subject Azacitidine Other / unclassified 32 mg/m2 —

Indications