drugset / Trial / NCT03858231
Opioids Versus Non-Opioids Postoperative After Knee Arthroscopic Surgery
RandomizedParallel-groupTriple-blindTreatment
Summary
The purpose of this study is to look at pain management with opioids versus non-opioids after knee arthroscopy. This study will determine 1) whether the most commonly used non-narcotic medications provide pain relief comparable with the most commonly prescribed narcotic medications in patients undergoing arthroscopic knee surgery, and 2) whether patients' characteristics (gender, pre-operative knee symptoms, workers compensation status and employment status) affect pain level following surgery or medication usage.
Timeline
- Start
- 2018-10-29
- Primary completion
- 2027-12
- Completion
- 2028-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Acetaminophen | Small molecule | 325 mg | — |
| Comparator | Hydrocodone | Unknown | 5 mg | — |
| Comparator | Hydrocodone | Unknown | 325 mg | — |
| Comparator | Ibuprofen | Small molecule | 600 mg | — |