drugset / Trial / NCT03858231

Opioids Versus Non-Opioids Postoperative After Knee Arthroscopic Surgery

NCT03858231

Phase 4 Recruiting 148 enrolled Sanford Health
RandomizedParallel-groupTriple-blindTreatment

Summary

The purpose of this study is to look at pain management with opioids versus non-opioids after knee arthroscopy. This study will determine 1) whether the most commonly used non-narcotic medications provide pain relief comparable with the most commonly prescribed narcotic medications in patients undergoing arthroscopic knee surgery, and 2) whether patients' characteristics (gender, pre-operative knee symptoms, workers compensation status and employment status) affect pain level following surgery or medication usage.

Timeline

Start
2018-10-29
Primary completion
2027-12
Completion
2028-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Acetaminophen Small molecule 325 mg
Comparator Hydrocodone Unknown 5 mg
Comparator Hydrocodone Unknown 325 mg
Comparator Ibuprofen Small molecule 600 mg