drugset / Trial / NCT03860662
The Effect of Oral Baclofen and Botulinum Toxin Treatments in Hemiplegic Spasticity on the Nociceptive Flexor Reflex
RandomizedParallel-groupDouble-blindTreatment
Summary
The purpose of this thesis is to research the effect of oral baclofen treatment and botulinum toxin injection treatments over the electromyographic nociceptive flexor reflex (NFR) threshold in hemiplegic patients with spasticity. The results of the study evaluated the Modified Ashworth Scale, joint range of motion, muscle strength, Brunnstrom stages, Barthel daily life activities index, electromyographic nociceptive flexor reflex (NFR) threshold.
Timeline
- Start
- 2018-05-26
- Primary completion
- 2019-03-21
- Completion
- 2019-04-21
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Baclofen | Small molecule | 5 mg | Oral |
| Comparator | Botulinum toxin type A | Protein / enzyme biologic | 300 iu | Intramuscular |
| Comparator | Botulinum toxin type A | Protein / enzyme biologic | 400 iu | Intramuscular |