drugset / Trial / NCT03872661

Neoadjuvant IBI308, Bevacizumab, Plus Pemetrexed and Carboplatin Followed by Surgery in Unresectable Stage III NSCLC

NCT03872661 ↗

Phase 2 Recruiting 36 enrolled Sun Yat-sen University
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to studying neoadjuvant IBI308, bevacizumab, plus pemetrexed and carboplatin followed by surgery to see how well it works in treating patients with unresectable stage III non-small cell lung cancer.

Timeline

Start
2019-03-01
Primary completion
2029-12-31
Completion
2029-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Bevacizumab Monoclonal antibody 15 mg/kg Intravenous
Subject Carboplatin Small molecule 5 unknown Intravenous
Subject Pemetrexed Small molecule 500 mg/m2 Intravenous
Subject Sintilimab Monoclonal antibody 200 mg Intravenous

Indications