drugset
drugset / Trial / NCT03877549

Dexamethasone Administered Via the Epidural Catheter as an Adjunct in Patients Undergoing Cesarean Delivery

NCT03877549 ↗

Phase 4 Withdrawn Henry Ford Health System
RandomizedParallel-groupTriple-blindTreatment

Summary

This study will evaluate the ability of dexamethasone to enhance labor epidurals when administered as an adjunct to local anesthetics via an epidural catheter. Patients undergoing elective cesarean sections will be randomized into three groups, each receiving the same combined spinal epidural (CSE). At surgical closure, Group 1 will receive 10cc bupivacaine 0.0625%, Group 2 will receive 10cc bupivacaine 0.0625% +4mg dexamethasone, and Group 3 will receive 10cc bupivacaine 0.0625% + 8mg dexamethasone (4mg). VAS, sedation, nausea, and satisfaction scoring will be measured on patient follow-up to compare the outcomes of the different treatment groups.

Timeline

Start
2019-05-24
Primary completion
2022-06-15
Completion
2022-06-15

Outcome

Outcome not reported

Stopped: “PI left Henry Ford Health before completion.”

Drugs

EvaluationDrugModalityDoseRoute
Subject Dexamethasone Small molecule 4 mg Other
Subject Dexamethasone Small molecule 8 mg Other

Indications

No indication recorded.