Study of Proton Therapy in Adjuvant Pancreatic Cancer

Phase 1 Completed 9 enrolled Georgetown University

Non-randomizedParallel-groupOpen-labelTreatment

Summary

This trial aims to determine a safe schedule of short-course proton beam radiation therapy with adjuvant mFOLFIRINOX for patients with resected pancreatic adenocarcinoma.

Timeline

Start: 2019-07-15
Primary completion: 2022-05-24
Completion: 2023-11-08

Publications

Weinberg BA, Wang H, Noel MS, He AR, Marshall JL, Weiner LM, Fishbein TM, Hodgins NE, Winslow ER, Jackson PG, Guerra JF, Aguila F, Unger KR. Phase 1 Study of Hypofractionated Proton Beam Radiation Therapy in Adjuvant Pancreatic Cancer (PROTON-PANC). Int J Radiat Oncol Biol Phys. 2024 Feb 1;118(2):362-367. doi: 10.1016/j.ijrobp.2023.09.015. Epub 2023 Sep 16.

Drugs

Evaluation	Drug	Modality	Dose	Route
Background	Irinotecan	Small molecule	150 mg/m2	Intravenous
Background	Oxaliplatin	Small molecule	85 mg/m2	Intravenous

Study of Proton Therapy in Adjuvant Pancreatic Cancer

Summary

Timeline

Publications

Drugs

Indications