drugset / Trial / NCT03892668

Intravenous Oxytocin Versus Tranexamic Acid in Reducing Blood Loss During Abdominal Myomectomy.

NCT03892668

Phase 4 Completed 150 enrolled Cairo University
RandomizedParallel-groupQuadruple-blindPrevention

Summary

Uterine leiomyomas (fibroids) are the most common benign tumors among women. Fibroids are found in approximately 20% of women over 35 years of age. In 20-50% of patients, fibroids may cause problems such as heavy menstrual bleeding, anemia, pelvic pain, pressure symptoms from extrinsic compression of the colorectal and urinary tract. Surgery is indicated for symptomatic uterine leiomyomas; hysterectomy for women who have completed childbearing (women \> 40 years old), and myomectomy for women \<40 years old who wish to preserve uterus and fertility.

Timeline

Start
2019-04-30
Primary completion
2020-02-01
Completion
2020-03-15

Drugs

EvaluationDrugModalityDoseRoute
Comparator Oxytocin Peptide 0.4 iu Intravenous
Subject Tranexamic Acid Small molecule 10 mg/kg Intravenous