drugset
drugset / Trial / NCT03894904

Papaverine vs Heparin for Peripheral Arterial Catheter Patency in Pediatric Patients

NCT03894904 ↗

Phase 4 Completed 100 enrolled The University of Texas Health Science Center, Houston
RandomizedParallel-groupTriple-blindPrevention

Summary

The purpose of this study is to compare intraoperative papaverine plus heparin to heparin alone for prevention of arterial spasm and maintenance of patency of peripheral arterial catheters during surgery in pediatric patients. The hypothesis is that periodic, intraoperative small-volume boluses of diluted papaverine plus heparin in peripheral arterial catheters of pediatric patients will prevent arterial spasm and help maintain patency of arterial catheters during general anesthesia.

Timeline

Start
2019-04-01
Primary completion
2020-10-10
Completion
2020-10-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Papaverine Small molecule 0.12 mg/ml Other
Subject Papaverine Small molecule 0.3 mg Other
Background Heparin Other / unclassified 2 unknown Other

Indications

No indication recorded.