drugset / Trial / NCT03905759

Prophylaxis Against Postoperative Atrial Fibrillation in Patients Undergoing On-pump CABG

NCT03905759

Phase 2/3 Unknown 48 enrolled doaa rashwan
RandomizedParallel-groupSingle-blindPrevention

Summary

Atrial fibrillation in the postoperative period of myocardial revascularization surgery (AF-POMR) occurs in 10% to 65% of patients, increasing morbidity and mortality after surgery. is associated with an increase in hospital length of stay, and, thus, in costs,and can cause serious clinical complications, such as hypotension, heart failure, stroke and other thromboembolic disorders.Although not completely understood, the electrophysiological mechanism of AF-POMR is believed to be reentry.

Timeline

Start
2019-04-03
Primary completion
2020-04-10
Completion
2020-04-10

Drugs

EvaluationDrugModalityDoseRoute
Comparator Amiodarone Small molecule 200 mg
Comparator Colchicine Small molecule 0.5 mg Oral
Comparator Dronedarone Small molecule 200 mg

Indications