drugset / Trial / NCT03905941

Relative Desirability of Metformin vs. Birth Control Pill in Treating PCOS in Women of Later Reproductive Age

NCT03905941

Phase 0 Withdrawn University of Virginia
RandomizedCrossoverQuadruple-blindTreatment

Summary

The goal of this study is to determine the relative desirability of metformin vs. oral combined hormonal contraceptives (OCs) in treating Polycystic Ovary Syndrome (PCOS) in women of later reproductive age. Polycystic Ovary Syndrome Questionnaire (PCOSQ) score will be used as a proxy for patient satisfaction. In light of their respective effects on the classic and metabolic facets of PCOS, metformin will provide non-inferior patient satisfaction compared to OCs in later reproductive age women with PCOS.

Timeline

Start
2021-08-23
Primary completion
2024-11-25
Completion
2024-11-25

Drugs

EvaluationDrugModalityDoseRoute
Subject Metformin Small molecule 2000 mg
Subject Norethindrone Unknown 1 mg
Subject ethinyl estradiol Small molecule 20 ug