drugset / Trial / NCT03905941
Relative Desirability of Metformin vs. Birth Control Pill in Treating PCOS in Women of Later Reproductive Age
RandomizedCrossoverQuadruple-blindTreatment
Summary
The goal of this study is to determine the relative desirability of metformin vs. oral combined hormonal contraceptives (OCs) in treating Polycystic Ovary Syndrome (PCOS) in women of later reproductive age. Polycystic Ovary Syndrome Questionnaire (PCOSQ) score will be used as a proxy for patient satisfaction. In light of their respective effects on the classic and metabolic facets of PCOS, metformin will provide non-inferior patient satisfaction compared to OCs in later reproductive age women with PCOS.
Timeline
- Start
- 2021-08-23
- Primary completion
- 2024-11-25
- Completion
- 2024-11-25
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Metformin | Small molecule | 2000 mg | — |
| Subject | Norethindrone | Unknown | 1 mg | — |
| Subject | ethinyl estradiol | Small molecule | 20 ug | — |