drugset / Trial / NCT03910504

Anaesthesia With or Without Rocuronium in Intubation and Intraoperative Nerve-monitoring During Thyroid Surgery.

NCT03910504

Completed 100 enrolled Federico Longhini
RandomizedParallel-groupTriple-blindOther

Summary

In this randomized controlled trial the investigators want to assess if, compared to controls, the administration of one single low-dose of rocuronium would increase the occurrence of absent or weak (i.e. amplitude \<100 μV) signal at V1 and R1, indicating a residual NMBA activity. In addition, we also recorded: 1) the occurrence of difficult laryngoscopy; 2) the time-to-intubation; 3) the occurrence of difficult intubation; 4) the number of intubation attempts; 5) the intubation failure rate; 6) the need for oxygenation between intubation attempts; 7) the lowest peripheral saturation in oxygen (SpO2); 8) the number of severe desaturations; 9) the time-to-V1 and 10) the number of post-surgical complications.

Timeline

Start
2019-04-17
Primary completion
2019-12-30
Completion
2019-12-30

Drugs

EvaluationDrugModalityDoseRoute
Comparator Rocuronium Other / unclassified 0.3 mg/kg Intravenous